E34.321 Primary insulin-like growth factor-1 (IGF-1) deficiency

Instructional Notes:

E34.321
Description: Primary insulin-like growth factor-1 (IGF-1) deficiency
Inclusion Term:
- Acid-labile subunit gene (IGFALS) defect
- Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
- Growth hormone insensitivity syndrome (GHIS)
- Insulin-like growth factor 1 gene (IGF1) defect
- Laron type short stature
- Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
- Signal transducer and activator of transcription 5B gene (STAT5b) defect
↓
E34.32
Description: Genetic causes of short stature
↓
E34.3
Description: Short stature due to endocrine disorder
Exclude1:
- achondroplastic short stature (Q77.4)
- hypochondroplastic short stature (Q77.4)
- nutritional short stature (E45)
- pituitary short stature (E23.0)
- progeria (E34.8)
- renal short stature (N25.0)
- Russell-Silver syndrome (Q87.19)
- short-limbed stature with immunodeficiency (D82.2)
- short stature (child) (R62.52)
- short stature in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
- short stature NOS (R62.52)
↓
E34
Description: Other endocrine disorders
Exclude1:
- pseudohypoparathyroidism (E20.1)
↓
E20-E35
Description: Disorders of other endocrine glands (E20-E35)
Exclude1:
- galactorrhea (N64.3)
- gynecomastia (N62)
↓
E00-E89
Description: Endocrine, nutritional and metabolic diseases
Exclude1:
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Notes:
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.